Aortic aneurysm, Aortic dissection, Aortic regurgitation, Aortic root aneurysm, Arachnodactyly, Ascending aortic dissection, Bicuspid aortic valve, Bruising susceptibility, Cardiomegaly, Carotid artery dilatation, Chest pain, Constipation, Coronary artery atherosclerosis, Cryptorchidism, Cutis marmorata, Descending aortic dissection, Descending thoracic aorta aneurysm, Diarrhea, Dilatation of the cerebral artery, Dural ectasia, Dysphagia, Exertional dyspnea, Hemoptysis, High, narrow palate, Hydronephrosis, Hydroureter, Hypertelorism, Hypertension, Hypoperistalsis, Hypovolemia, Intestinal malrotation, Intestinal pseudo-obstruction, Ischemic stroke, Malnutrition, Megacystis, Microcolon, Mucoid extracellular matrix accumulation, Multicystic kidney dysplasia, Nausea and vomiting, Neoplasm of the heart, Omphalocele, Pancreatitis, Paroxysmal dyspnea, Patent ductus arteriosus, Peripheral arterial stenosis, Pes planus, Pneumothorax, Polyhydramnios, Prenatal maternal abnormality, Retrognathia, Scoliosis, Sepsis, Stroke, Subarachnoid hemorrhage, Tall stature, Transient ischemic attack, Umbilical hernia, Urinary retention, Vesicoureteral reflux, Vomiting

decreased systemic arterial diastolic blood pressure, decreased systemic arterial systolic blood pressure, distended ileum, distended jejunum, growth/size/body region phenotype, impaired smooth muscle contractility, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, premature death, prenatal lethality, incomplete penetrance, small intestinal inflammation