Monarch Ortholog Phenotypes
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Human (44 sources):
Abnormal heart morphology,
Abnormal rib morphology,
Abnormal sternum morphology,
Abnormality of the bladder,
Abnormality of the skin,
Abnormality of the ureter,
Abnormality of the uterus,
Anal atresia,
Aplasia of the abdominal wall musculature,
Aplasia/Hypoplasia of the lungs,
Atrial septal defect,
Cognitive impairment,
Congenital hip dislocation,
Congenital posterior urethral valve,
Constipation,
Cryptorchidism,
Decreased fertility,
Decreased testicular size,
Drug-induced agranulocytosis,
Failure to thrive,
Hallucinations,
Hydronephrosis,
Hydroureter,
Intestinal atresia,
Intestinal malrotation,
Multicystic kidney dysplasia,
Oligohydramnios,
Patent ductus arteriosus,
Pectus carinatum,
Pectus excavatum,
Prune belly,
Recurrent respiratory infections,
Recurrent urinary tract infections,
Renal insufficiency,
Scoliosis,
Talipes equinovarus,
Tetralogy of Fallot,
Urethral valve,
Urogenital sinus anomaly,
Ventricular septal defect,
Vertebral segmentation defect,
Vesicoureteral reflux,
Volvulus,
Xerostomia
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Mouse (29 sources):
abnormal brain wave pattern,
abnormal frequency of paradoxical sleep,
abnormal histamine physiology,
abnormal inhibitory postsynaptic currents,
abnormal submandibular gland physiology,
behavior/neurological phenotype,
cardiovascular system phenotype,
decreased body size,
decreased bronchoconstrictive response,
decreased circulating glucose level,
decreased digestive secretion,
decreased food intake,
decreased glucagon secretion,
decreased gonadal fat pad weight,
decreased insulin secretion,
decreased salivation,
decreased vasodilation,
growth/size/body region phenotype,
homeostasis/metabolism phenotype,
impaired contextual conditioning behavior,
impaired contractility of ileal smooth muscle,
impaired contractility of urinary bladder detrusor smooth muscle,
impaired cued conditioning behavior,
impaired smooth muscle contractility,
improved glucose tolerance,
increased fluid intake,
increased insulin secretion,
increased insulin sensitivity,
nervous system phenotype
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View all ortholog results at Monarch
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