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XB-GENEPAGE-943445
p2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal development of neural crest (2 sources), abnormal gastrulation (2 sources), abnormal incomplete closing of the blastopore (2 sources), decreased size of the head (2 sources), abnormal development of otic vesicle (1 source), decreased size of the eye (1 source), increased pigmentation in the animal hemisphere (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: p2ry4 manipulated (13 sources) |
Computed annotations: p2ry4 assayed (4 sources) |
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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spina bifida (3AP sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + p2ry4 TALEN (15 sources), Xla Wt + p2ry4 (3 sources) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Mouse (2 sources): abnormal digestive secretion, perinatal lethality, incomplete penetrance |