xrcc4 Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (5)

Nucleotides (87)

Interactants (47)

XB-GENEPAGE-943955

Gene Symbol: xrcc4 Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 4

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (61 sources): Abnormal circulating lipid concentration, Acanthosis nigricans, Anemia, Apraxia, Ataxia, Broad nasal tip, Broad-based gait, Cataract, Cerebellar vermis atrophy, Clinodactyly, Cognitive impairment, Congenital blindness, Convex nasal ridge, Cryptorchidism, Deeply set eye, Delayed speech and language development, Diabetes mellitus, Dilated cardiomyopathy, Disproportionate short-limb short stature, Drug-induced agranulocytosis, Dysarthria, Dysdiadochokinesis, Dysmetria, Ectopic kidney, Global developmental delay, Hepatic steatosis, High forehead, High pitched voice, Hypertriglyceridemia, Hypotelorism, Hypothyroidism, Immunodeficiency, Insulin resistance, Insulin-resistant diabetes mellitus, Intrauterine growth retardation, Long face, Long nose, Lymphopenia, Malar prominence, Microcephaly, Micrognathia, Micropenis, Nystagmus, Pes cavus, Primary gonadal insufficiency, Prominent nasal bridge, Renal hypoplasia, Retinal detachment, Sensorineural hearing impairment, Sensory neuropathy, Severe short-limb dwarfism, Short chin, Short stature, Simplified gyral pattern, Sloping forehead, Sparse hair, Tooth malposition, Triangular face, Truncal obesity, Unilateral renal agenesis, Ventriculomegaly [+]
Mouse (8 sources): abnormal cerebral cortex morphology, abnormal class switch recombination, fetal growth retardation, increased cellular sensitivity to gamma-irradiation, increased neuron apoptosis, lethality throughout fetal growth and development, complete penetrance, spontaneous chromosome breakage, thin cerebral cortex
View all ortholog results at Monarch