abnormal umbilical cord morphology, abnormal visceral yolk sac morphology, abnormal vitelline vasculature morphology, absent intersomitic vessels, absent marginal zone B cells, decreased CD4-positive, alpha beta T cell number, decreased double-positive T cell number, decreased embryo size, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased transitional stage T2 B cell number, delayed heart development, digestive/alimentary phenotype, distended pericardium, embryonic lethality during organogenesis, complete penetrance, failure of vascular branching, forestomach hypoplasia, increased follicular B cell number, increased hematopoietic stem cell number, increased neutrophil cell number, increased spleen red pulp amount, increased spleen weight, increased transitional stage T1 B cell number, myeloid hyperplasia, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, small first pharyngeal arch, small thymus, spleen hyperplasia