| Monarch Ortholog Phenotypes
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Mouse (22 sources):
abnormal craniofacial morphology,
acanthosis,
decreased body size,
decreased hair follicle number,
decreased survivor rate,
dermatitis,
embryonic lethality, incomplete penetrance,
homeostasis/metabolism phenotype,
immune system phenotype,
increased T cell proliferation,
increased anti-double stranded DNA antibody level,
increased autoantibody level,
increased circulating alanine transaminase level,
increased circulating interferon-gamma level,
increased circulating interleukin-2 level,
increased circulating interleukin-4 level,
increased kidney cell proliferation,
increased mesangial cell number,
increased susceptibility to systemic lupus erythematosus,
perinatal lethality, incomplete penetrance,
premature death,
skin lesions
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These phenotypes are associated with this gene with a has phenotype relation via Monarch.