ggcx Phenotypes

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Phenotypes

XB-GENEPAGE-949714

Gene Symbol: ggcx Gene Name: gamma-glutamyl carboxylase

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (28 sources): Abnormal bleeding, Abnormal fundus morphology, Abnormality of coagulation, Abnormality of the optic nerve, Absent retinal pigment epithelium, Angioid streaks of the fundus, Atherosclerosis, Attenuation of retinal blood vessels, Bruising susceptibility, Cutis laxa, Dilatation of the cerebral artery, Ecchymosis, Epiphyseal stippling, Epistaxis, Increased number of skin folds, Joint hemorrhage, Nyctalopia, Papule, Prolonged partial thromboplastin time, Prolonged prothrombin time, Reduced factor IX activity, Reduced factor VII activity, Reduced factor X activity, Redundant skin, Rod-cone dystrophy, Short distal phalanx of finger, Short nose, Strabismus [+]
Mouse (20 sources): abnormal circulating osteocalcin level, decreased circulating osteocalcin level, decreased epididymal fat pad weight, decreased susceptibility to diet-induced obesity, homeostasis/metabolism phenotype, impaired blood coagulation, improved glucose tolerance, increased carbon dioxide production, increased insulin sensitivity, increased oxygen consumption, lethality throughout fetal growth and development, incomplete penetrance, neonatal lethality, complete penetrance, pregnancy-related premature death, premature death, reproductive system phenotype, skeleton phenotype, subcutaneous hemorrhage, thin body, uterine hemorrhage, vaginal hemorrhage [+]
View all ortholog results at Monarch