Monarch Ortholog Phenotypes
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Mouse (27 sources):
decreased CD8-positive, naive alpha-beta T cell number,
decreased Ly6C-positive mature NK cell number,
decreased NK T cell number,
decreased T-helper cell number,
decreased effector memory CD8-positive, alpha-beta T cell number,
decreased erythrocyte cell number,
decreased hematocrit,
decreased hemoglobin content,
decreased mature B cell number,
increased CD11b-low dendritic cell number,
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased CD4-positive, alpha beta T cell number,
increased CD4-positive, alpha-beta memory T cell number,
increased CD5-positive gamma-delta T cell number,
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased KLRG1-positive T-helper cell number,
increased dendritic cell number,
increased effector memory T-helper cell number,
increased gamma-delta T cell number,
increased granulocyte number,
increased marginal zone B cell number,
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number,
increased memory-marker CD4-negative NK T cell number,
increased memory-marker gamma-delta T cell number,
increased plasma cell number,
increased plasmacytoid dendritic cell number,
vertebral transformation
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