| Monarch Ortholog Phenotypes
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Human (1 source):
Eczema
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Mouse (30 sources):
abnormal angiogenesis,
abnormal astrocyte morphology,
abnormal brain vasculature morphology,
abnormal chorioallantoic fusion,
abnormal embryo size,
abnormal embryo turning,
abnormal embryonic/fetal subventricular zone morphology,
abnormal extraembryonic tissue morphology,
abnormal pericardial cavity morphology,
abnormal placenta morphology,
abnormal placenta vasculature,
abnormal placental labyrinth vasculature morphology,
abnormal radial glial cell morphology,
abnormal skin coloration,
abnormal vascular endothelial cell morphology,
abnormal visceral yolk sac morphology,
abnormal vitelline vasculature morphology,
absent floor plate,
decreased embryo size,
decreased spleen weight,
embryonic lethality during organogenesis, incomplete penetrance,
failure of vascular branching,
impaired basement membrane formation,
increased vascular endothelial cell number,
no abnormal phenotype detected,
palatal shelves fail to meet at midline,
pale yolk sac,
postnatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
thin placenta labyrinth
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.