| Monarch Ortholog Phenotypes
|
Human (39 sources):
Abnormal circulating enzyme concentration,
Abnormality of metabolism/homeostasis,
Abnormality of the dentition,
Abnormality of the skeletal system,
Acrocyanosis,
Anemia,
Arterial occlusion,
Atherosclerosis,
Atrioventricular block,
Bone pain,
Calcinosis,
Calcinosis cutis,
Calcium oxalate nephrolithiasis,
Choroidal neovascularization,
Cutis marmorata,
Decreased glomerular filtration rate,
Dysuria,
Enuresis,
Failure to thrive,
Gangrene,
Hematuria,
Hyperoxaluria,
Increased bone mineral density,
Intermittent claudication,
Metabolic acidosis,
Nephrocalcinosis,
Nephrolithiasis,
Optic atrophy,
Optic neuropathy,
Pathologic fracture,
Peripheral arterial stenosis,
Peripheral neuropathy,
Raynaud phenomenon,
Recurrent urinary tract infections,
Renal insufficiency,
Retinal crystals,
Retinopathy,
Stage 5 chronic kidney disease,
Stroke
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|
Mouse (3 sources):
crystalluria,
increased physiological sensitivity to xenobiotic,
urolithiasis
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.