| Monarch Ortholog Phenotypes
|
Human (24 sources):
Abnormal dental enamel morphology,
Abnormality of blood and blood-forming tissues,
Acanthosis nigricans,
Cholangitis,
Cholestasis,
Dry skin,
Enamel hypoplasia,
Epidermal acanthosis,
Hepatomegaly,
Hypodontia,
Ichthyosis,
Jaundice,
Oligodontia,
Orthokeratosis,
Parakeratosis,
Portal hypertension,
Scarring alopecia of scalp,
Sparse body hair,
Sparse eyelashes,
Splenomegaly,
Thick hair,
obsolete Hypotrichosis,
obsolete Hypotrichosis of the scalp,
obsolete Sparse and thin eyebrow
[+]
|
|
Mouse (6 sources):
abnormal embryo size,
abnormal startle reflex,
impaired skin barrier function,
increased startle reflex,
neonatal lethality, complete penetrance,
preweaning lethality, complete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.