| Monarch Ortholog Phenotypes
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Human (17 sources):
Allergic rhinitis,
Arthralgia,
Asthma,
Bronchiolitis,
Cataract,
Cellulitis,
Corneal erosion,
Decreased circulating IgA level,
Decreased circulating total IgM,
Erythema,
[+]
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Mouse (45 sources):
abnormal bone mineralization,
abnormal dendritic cell chemotaxis,
abnormal dendritic cell morphology,
abnormal dendritic cell physiology,
abnormal foot pad morphology,
abnormal humoral immune response,
abnormal osteoclast differentiation,
arrested B cell differentiation,
chronic inflammation,
decreased B cell proliferation,
decreased B-1a cell number,
decreased B-2 B cell number,
decreased CD8-positive, naive alpha-beta T cell number,
decreased circulating free fatty acids level,
decreased erythrocyte cell number,
decreased follicular B cell number,
decreased hematocrit,
decreased hemoglobin content,
decreased interferon-gamma secretion,
decreased mature B cell number,
decreased osteoclast cell number,
decreased pre-B cell number,
decreased susceptibility to induced arthritis,
decreased transitional stage B cell number,
decreased tumor necrosis factor secretion,
dermatitis,
immune system phenotype,
impaired natural killer cell mediated cytotoxicity,
increased B cell apoptosis,
increased B cell proliferation,
increased B-1a cell number,
increased IgG1 level,
increased bone mineral content,
increased effector memory CD8-positive, alpha-beta T cell number,
increased immature B cell number,
increased lean body mass,
increased pre-B cell number,
increased pro-B cell number,
increased susceptibility to Herpesvirales infection,
increased total body fat amount,
increased trabecular bone thickness,
increased trabecular bone volume,
increased transitional stage T2 B cell number,
premature death,
spleen hyperplasia
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View all ortholog results at Monarch
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These phenotypes are associated with this gene with a has phenotype relation via Monarch.