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Summary Expression Phenotypes Gene Literature (149) GO Terms (18) Nucleotides (185) Proteins (31) Interactants (808) Wiki

pc.1     pyruvate carboxylase, gene 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pc.1 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources): Clonus, Generalized hypotonia, Global developmental delay, Hepatomegaly, Hyperalaninemia, Hypoglycemia, Hypotonia, Increased circulating lactate concentration, Increased serum pyruvate, Intellectual disability, [+]
Mouse (5 sources): decreased lean body mass, decreased red blood cell distribution width, increased grip strength, increased total body fat amount, preweaning lethality, complete penetrance

View all ortholog results at Monarch