| Monarch Ortholog Phenotypes
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Human (23 sources):
Abnormal nasal morphology,
Chronic kidney disease,
Congenital posterior urethral valve,
Dysuria,
Eczematoid dermatitis,
Enuresis nocturna,
Failure to thrive,
Fetal pyelectasis,
Hydronephrosis,
Hypertelorism,
Hypertension,
Lethargy,
Oligohydramnios,
Pyelonephritis,
Recurrent urinary tract infections,
Renal insufficiency,
Retrognathia,
Stage 5 chronic kidney disease,
Unilateral renal dysplasia,
Urethral stenosis,
Urinary incontinence,
Urinary retention,
Vesicoureteral reflux
[+]
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Mouse (14 sources):
abnormal maxillary shelf morphology,
abnormal palate development,
abnormal prepulse inhibition,
abnormal pterygoid process morphology,
absent palatine bone,
decreased birth body size,
decreased exploration in new environment,
increased prepulse inhibition,
meteorism,
neonatal lethality, complete penetrance,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.