| Monarch Ortholog Phenotypes
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Human (22 sources):
Abnormal circulating calcium-phosphate regulating hormone concentration,
Abnormality of retinal pigmentation,
Amelogenesis imperfecta,
Astigmatism,
Chorioretinal coloboma,
Chronic kidney disease,
Hematuria,
Hypercalciuria,
Hypermagnesiuria,
Hypomagnesemia,
Macular coloboma,
Myopia,
Nephrocalcinosis,
Nephrolithiasis,
Nephropathy,
Nystagmus,
Recurrent urinary tract infections,
Renal calcium wasting,
Renal magnesium wasting,
Rod-cone dystrophy,
Strabismus,
Umbilical hernia
[+]
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|
Mouse (7 sources):
abnormal Schwann cell morphology,
abnormal exploration in a new environment,
abnormal sleep behavior,
decreased exploration in new environment,
shortened PQ interval,
shortened RR interval,
shortened ST segment
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.