Mouse (54 sources):
abnormal DNA replication,
abnormal Paneth cell morphology,
abnormal blastocyst morphology,
abnormal double-strand DNA break repair,
abnormal embryo development,
abnormal embryonic erythropoiesis,
abnormal embryonic hematopoiesis,
abnormal lung development,
abnormal spleen B cell follicle morphology,
abnormal spleen marginal zone morphology,
abnormal telomere morphology,
absent inner cell mass,
aneuploidy,
chromosomal instability,
chronic inflammation,
decreased cell proliferation,
decreased embryo size,
decreased fibroblast proliferation,
decreased lung weight,
decreased trophoblast giant cell number,
embryonic growth retardation,
embryonic lethality before implantation, complete penetrance,
embryonic lethality during organogenesis, complete penetrance,
immune system phenotype,
increased B cell derived lymphoma incidence,
increased anti-double stranded DNA antibody level,
increased anti-nuclear antigen antibody level,
increased cellular sensitivity to gamma-irradiation,
increased cellular sensitivity to methylmethanesulfonate,
increased gonad tumor incidence,
increased kidney apoptosis,
increased liver tumor incidence,
increased lung adenoma incidence,
increased lung apoptosis,
increased lung tumor incidence,
increased plasma cell number,
increased sensitivity to induced cell death,
increased susceptibility to autoimmune disorder,
increased thymus tumor incidence,
increased tumor incidence,
increased white adipose tissue amount,
inner cell mass degeneration,
lymphoid hyperplasia,
neonatal lethality, complete penetrance,
no abnormal phenotype detected,
open neural tube,
pale liver,
pale spleen,
premature death,
prenatal lethality, complete penetrance,
renal glomerular immunoglobulin deposits,
spontaneous chromosome breakage,
thick lung-associated mesenchyme,
thymus atrophy
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