Monarch Ortholog Phenotypes
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Mouse (37 sources):
abnormal cochlear hair cell stereociliary bundle morphology,
abnormal glomerular capillary endothelium morphology,
abnormal glomerular endothelium fenestra morphology,
abnormal lens development,
abnormal podocyte foot process morphology,
abnormal prepulse inhibition,
abnormal pulmonary alveolus morphology,
abnormal renal glomerulus morphology,
abnormal startle reflex,
absent startle reflex,
bidirectional circling,
circling,
cochlear ganglion degeneration,
cochlear inner hair cell degeneration,
cochlear outer hair cell degeneration,
deafness,
decreased body length,
decreased body size,
decreased circulating glucose level,
decreased digestive secretion,
decreased eosinophil cell number,
decreased prepulse inhibition,
decreased startle reflex,
decreased susceptibility to hepatic steatosis,
head bobbing,
head tossing,
impaired swimming,
increased aggression towards male mice,
increased or absent threshold for auditory brainstem response,
increased respiratory quotient,
increased stomach pH,
increased susceptibility to injury,
increased susceptibility to weight loss,
limb grasping,
organ of Corti degeneration,
podocyte foot process effacement,
vestibular hair cell degeneration
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