mbnl2 Phenotypes

Phenotypes

XB-GENEPAGE-961078

Gene Symbol: mbnl2 Gene Name: muscleblind-like splicing regulator 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mbnl2 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (14 sources): abnormal CNS synaptic transmission, abnormal excitatory postsynaptic potential, abnormal paradoxical sleep pattern, abnormal spatial reference memory, decreased body size, decreased skeletal muscle fiber size, fragmentation of sleep/wake states, impaired synaptic plasticity, increased frequency of paradoxical sleep, increased susceptibility to pharmacologically induced seizures, muscle phenotype, postnatal lethality, incomplete penetrance, reduced long term potentiation, skeletal muscle interstitial fibrosis [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (14 sources): abnormal CNS synaptic transmission, abnormal excitatory postsynaptic potential, abnormal paradoxical sleep pattern, abnormal spatial reference memory, decreased body size, decreased skeletal muscle fiber size, fragmentation of sleep/wake states, impaired synaptic plasticity, increased frequency of paradoxical sleep, increased susceptibility to pharmacologically induced seizures, [+]