slc40a1 Phenotypes

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Phenotypes

Gene Literature (6)

Nucleotides (143)

Interactants (7)

XB-GENEPAGE-963434

Gene Symbol: slc40a1 Gene Name: solute carrier family 40 (iron-regulated transporter), member 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: slc40a1 assayed (12 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (19 sources): Abdominal pain, Anemia, Arrhythmia, Arthralgia, Cardiomyopathy, Cataract, Cirrhosis, Congenital hepatic fibrosis, Fatigue, Generalized hyperpigmentation, Glucose intolerance, Hepatic steatosis, Impaired glucose tolerance, Impotence, Increased circulating ferritin concentration, Joint dislocation, Joint swelling, Limitation of joint mobility, Osteoarthritis [+]
Mouse (44 sources): abnormal enzyme/coenzyme level, abnormal forebrain development, abnormal macrophage physiology, abnormal pancreatic acinar cell morphology, abnormal spleen development, decreased body size, decreased bone mineral content, decreased circulating iron level, decreased circulating unsaturated transferrin level, decreased embryo size, decreased hematocrit, decreased hemoglobin content, decreased intestinal iron level, decreased lean body mass, decreased liver iron level, decreased mean corpuscular hemoglobin, decreased mean corpuscular volume, decreased spleen iron level, decreased thermal nociceptive threshold, embryonic lethality between implantation and somite formation, incomplete penetrance, embryonic lethality between somite formation and embryo turning, complete penetrance, embryonic lethality prior to tooth bud stage, hematopoietic system phenotype, hemochromatosis, homeostasis/metabolism phenotype, increased circulating ferritin level, increased circulating iron level, increased circulating lipase level, increased circulating unsaturated transferrin level, increased erythrocyte cell number, increased heart iron level, increased intestinal iron level, increased kidney iron level, increased pancreas iron level, increased spleen iron level, increased splenocyte apoptosis, leptocytosis, nervous system phenotype, oxidative stress, premature death, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, small spleen, vision/eye phenotype [+]
View all ortholog results at Monarch