neurod1 Phenotypes

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Phenotypes

Gene Literature (176)

Nucleotides (166)

Interactants (824)

XB-GENEPAGE-963756

Gene Symbol: neurod1 Gene Name: neuronal differentiation 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: neurod1 manipulated (3 sources), neurod1 assayed (5 sources)
Computed annotations: neurod1 assayed (5 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + neurod1 (2 sources), Xla Wt + neurod1 (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (25 sources): Abnormal C-peptide level, Abnormal insulin level, Abnormal oral glucose tolerance, Abnormality of the genitourinary system, Abnormality of the kidney, Elevated hemoglobin A1c, Exocrine pancreatic insufficiency, Glucose intolerance, Glycosuria, Hepatocellular adenoma, Hyperglycemia, Hyperinsulinemic hypoglycemia, Hypoinsulinemia, Insulin-resistant diabetes mellitus, Intrauterine growth retardation, Large for gestational age, Maturity-onset diabetes of the young, Neonatal hypoglycemia, Nephropathy, Obesity, Overweight, Pancreatic hypoplasia, Renal cyst, Retinopathy, Transient neonatal diabetes mellitus [+]
Mouse (59 sources): abnormal Muller cell morphology, abnormal Purkinje cell morphology, abnormal amacrine cell morphology, abnormal brain wave pattern, abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal dentate gyrus morphology, abnormal hippocampus CA4 region morphology, abnormal hippocampus development, abnormal hippocampus granule cell layer, abnormal hippocampus granule cell morphology, abnormal intestinal enteroendocrine cell morphology, abnormal intestinal mucosa morphology, abnormal lung epithelium morphology, abnormal neuron differentiation, abnormal pancreatic acinar cell morphology, abnormal pancreatic beta cell morphology, abnormal retina apoptosis, abnormal retina bipolar cell morphology, abnormal retina cone cell morphology, abnormal retina ganglion cell morphology, abnormal retina ganglion layer morphology, abnormal retina inner nuclear layer morphology, abnormal sensory neuron innervation pattern, abnormal vestibular ganglion morphology, abnormal vestibulocochlear ganglion morphology, absent cochlear ganglion, absent dentate gyrus, absent endocochlear potential, absent pancreatic islets, circling, deafness, decreased Purkinje cell number, decreased body size, decreased pancreatic alpha cell number, decreased pancreatic delta cell number, decreased sensory neuron number, decreased solitary pulmonary neuroendocrine cell number, head tilt, head tossing, hearing/vestibular/ear phenotype, homeostasis/metabolism phenotype, impaired balance, impaired lung alveolus development, increased number of pulmonary neuroendocrine bodies, increased pancreas apoptosis, increased retina apoptosis, increased retina ganglion cell number, nervous system phenotype, no abnormal phenotype detected, overexpanded pulmonary alveoli, pancreatic acinar cell zymogen granule accumulation, perinatal lethality, complete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, reduced cochlear modiolus, small cerebellum, sporadic seizures, thin external granule cell layer [+]
View all ortholog results at Monarch