| Monarch Ortholog Phenotypes
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Human (26 sources):
Abnormality of epiphysis morphology,
Arthralgia,
Barrel-shaped chest,
Coxa vara,
Disproportionate short stature,
Disproportionate short-trunk short stature,
Hip osteoarthritis,
Hump-shaped mound of bone in central and posterior portions of vertebral endplate,
Hypoplasia of the capital femoral epiphysis,
Hypoplasia of the odontoid process,
Hypoplastic iliac wing,
Irregular epiphyses,
Kyphosis,
Limitation of joint mobility,
Lumbar hyperlordosis,
Opacification of the corneal stroma,
Osteoarthritis,
Platyspondyly,
Scoliosis,
Shield chest,
Short femoral neck,
Short neck,
Short thorax,
Spondyloepiphyseal dysplasia,
Thoracic kyphosis,
Upper limb undergrowth
[+]
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Mouse (6 sources):
decreased bronchoconstrictive response,
decreased pulmonary ventilation,
decreased startle reflex,
hydrometra,
increased pulmonary respiratory rate,
increased pulmonary ventilation
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.