Monarch Ortholog Phenotypes
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Mouse (27 sources):
abnormal T cell differentiation,
abnormal apoptosis,
abnormal cell nucleus count,
abnormal cell nucleus morphology,
abnormal embryonic tissue morphology,
abnormal keratinocyte physiology,
abnormal mitotic spindle morphology,
abnormal oxidative phosphorylation,
abnormal thymus corticomedullary boundary morphology,
absent blastocoele,
absent trophoblast giant cells,
binucleate,
decreased cellular sensitivity to ultraviolet irradiation,
decreased double-negative T cell number,
decreased double-positive T cell number,
decreased incidence of tumors by chemical induction,
decreased thymocyte number,
embryonic lethality before implantation, complete penetrance,
embryonic lethality between implantation and somite formation, complete penetrance,
failure of blastocyst to hatch from the zona pellucida,
increased T cell apoptosis,
increased double-negative T cell number,
increased susceptibility to injury,
inner cell mass degeneration,
no abnormal phenotype detected,
small lymph nodes,
small thymus
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