arg1 Phenotypes

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Phenotypes

Gene Literature (13)

Nucleotides (283)

Interactants (619)

XB-GENEPAGE-966912

Gene Symbol: arg1 Gene Name: arginase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: arg1 assayed (1 source)
Computed annotations: arg1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (18 sources): Anorexia, Behavioral abnormality, Diaminoaciduria, EEG abnormality, Failure to thrive, Global developmental delay, Hemiplegia/hemiparesis, Hepatic fibrosis, Hyperactivity, Hyperammonemia, Intellectual disability, Intellectual disability, severe, Irritability, Neurological speech impairment, Oroticaciduria, Progressive spastic quadriplegia, Seizure, Vomiting [+]
Mouse (14 sources): abnormal blood homeostasis, abnormal hepatobiliary system morphology, abnormal hepatocyte morphology, abnormal macrophage physiology, abnormal nitric oxide homeostasis, decreased susceptibility to bacterial infection, decreased susceptibility to parasitic infection, increased circulating citrulline level, increased macrophage nitric oxide production, nervous system phenotype, no abnormal phenotype detected, pale liver, postnatal lethality, postnatal lethality, complete penetrance [+]
View all ortholog results at Monarch