pls1 Phenotypes

Phenotypes

XB-GENEPAGE-967637

Gene Symbol: pls1 Gene Name: plastin 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pls1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (18 sources): abnormal hair cell mechanoelectric transduction, abnormal inner hair cell stereociliary bundle morphology, abnormal intestinal epithelium morphology, abnormal intestine physiology, abnormal outer hair cell stereociliary bundle morphology, behavior/neurological phenotype, decreased inner hair cell stereocilia number, decreased small intestinal microvillus size, fused outer hair cell stereocilia, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased enterocyte apoptosis, increased or absent threshold for auditory brainstem response, increased susceptibility to colitis induced morbidity/mortality, increased susceptibility to induced colitis, reproductive system phenotype, short inner hair cell stereocilia, thin cochlear hair cell stereocilia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (18 sources): abnormal hair cell mechanoelectric transduction, abnormal inner hair cell stereociliary bundle morphology, abnormal intestinal epithelium morphology, abnormal intestine physiology, abnormal outer hair cell stereociliary bundle morphology, behavior/neurological phenotype, decreased inner hair cell stereocilia number, decreased small intestinal microvillus size, fused outer hair cell stereocilia, growth/size/body region phenotype, [+]