npr1 Phenotypes

Phenotypes

XB-GENEPAGE-970521

Gene Symbol: npr1 Gene Name: natriuretic peptide receptor 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: npr1 manipulated (1 source)
Computed annotations: npr1 assayed (7 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + npr1 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (25 sources): abnormal cardiac muscle relaxation, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal sex gland physiology, abnormal systemic arterial blood pressure, abnormal vasodilation, cardiac hypertrophy, cardiac interstitial fibrosis, decreased metastatic potential, decreased myocardial infarct size, decreased sensitivity to induced morbidity/mortality, decreased systemic arterial blood pressure, decreased systemic arterial systolic blood pressure, dilated heart left ventricle, increased circulating atrial natriuretic factor, increased heart weight, increased mean systemic arterial blood pressure, increased metastatic potential, increased sensitivity to induced morbidity/mortality, increased systemic arterial blood pressure, increased systemic arterial diastolic blood pressure, increased systemic arterial systolic blood pressure, premature death, pulmonary embolism, salt-resistant hypertension [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (25 sources): abnormal cardiac muscle relaxation, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal sex gland physiology, abnormal systemic arterial blood pressure, abnormal vasodilation, cardiac hypertrophy, cardiac interstitial fibrosis, decreased metastatic potential, decreased myocardial infarct size, [+]