s1pr1 Phenotypes

Phenotypes

XB-GENEPAGE-977002

Gene Symbol: s1pr1 Gene Name: sphingosine-1-phosphate receptor 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: s1pr1 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (31 sources): abnormal NK cell differentiation, abnormal aorta endothelium morphology, abnormal aorta smooth muscle morphology, abnormal artery morphology, abnormal axon morphology, abnormal diencephalon morphology, abnormal leukocyte migration, abnormal limb morphology, abnormal lymphocyte physiology, abnormal pericardial cavity morphology, abnormal pericyte morphology, abnormal telencephalon morphology, abnormal vascular branching morphogenesis, abnormal vascular endothelial cell morphology, abnormal vascular smooth muscle morphology, abnormal visceral yolk sac morphology, decreased physiological sensitivity to xenobiotic, decreased susceptibility to experimental autoimmune encephalomyelitis, embryonic lethality during organogenesis, complete penetrance, enlarged pericardium, immune system phenotype, impaired fibroblast cell migration, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased neuron apoptosis, increased vascular endothelial cell apoptosis, lethality throughout fetal growth and development, complete penetrance, no abnormal phenotype detected, pericardial edema, poor arterial differentiation, vascular smooth muscle hypoplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (31 sources): abnormal NK cell differentiation, abnormal aorta endothelium morphology, abnormal aorta smooth muscle morphology, abnormal artery morphology, abnormal axon morphology, abnormal diencephalon morphology, abnormal leukocyte migration, abnormal limb morphology, abnormal lymphocyte physiology, abnormal pericardial cavity morphology, [+]