nlgn3 Phenotypes

Phenotypes

XB-GENEPAGE-977260

Gene Symbol: nlgn3 Gene Name: neuroligin 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: nlgn3 assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (32 sources): abnormal excitatory postsynaptic potential, abnormal glutamate-mediated receptor currents, abnormal inhibitory postsynaptic currents, abnormal learning/memory/conditioning, abnormal miniature excitatory postsynaptic currents, abnormal miniature inhibitory postsynaptic currents, abnormal righting response, abnormal social investigation, abnormal spatial learning, absent long term depression, behavior/neurological phenotype, decreased brain size, decreased excitatory postsynaptic current amplitude, decreased grip strength, decreased locomotor activity, decreased spleen weight, decreased startle reflex, decreased vertical activity, decreased vocalization, enhanced coordination, enhanced learning, impaired contextual conditioning behavior, impaired cued conditioning behavior, impaired olfaction, impaired synaptic plasticity, increased CNS synapse formation, increased excitatory postsynaptic current amplitude, increased growth rate, increased thigmotaxis, nervous system phenotype, no abnormal phenotype detected, reduced AMPA-mediated synaptic currents [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (32 sources): abnormal excitatory postsynaptic potential, abnormal glutamate-mediated receptor currents, abnormal inhibitory postsynaptic currents, abnormal learning/memory/conditioning, abnormal miniature excitatory postsynaptic currents, abnormal miniature inhibitory postsynaptic currents, abnormal righting response, abnormal social investigation, abnormal spatial learning, absent long term depression, [+]