| Monarch Ortholog Phenotypes
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Human (23 sources):
Abnormality of the genital system,
Abnormality of the hand,
Abnormality of the urinary system,
Acute leukemia,
Anemia,
Arrhythmia,
Cleft palate,
Delayed puberty,
Depressed nasal ridge,
Fatigue,
Growth delay,
Hypertelorism,
Increased mean corpuscular volume,
Macrocytic anemia,
Migraine,
Neoplasm,
Neutropenia,
Pallor,
Short nose,
Short stature,
Thick lower lip vermilion,
Thick upper lip vermilion,
Wide nasal bridge
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Mouse (23 sources):
abnormal cerebral cortex morphology,
abnormal erythropoiesis,
abnormal melanoblast morphology,
abnormal spatial working memory,
abnormal sternebra morphology,
abnormal vertebral arch morphology,
abnormal vertebral transverse process morphology,
asymmetric sternocostal joints,
belly spot,
cervical vertebral transformation,
curly tail,
decreased body size,
decreased caudal vertebrae number,
decreased neural crest cell number,
delayed optic fissure closure,
embryonic growth retardation,
increased neuron apoptosis,
kinked tail,
lumbar vertebral transformation,
premature death,
small hippocampus,
thin cerebral cortex,
uveal coloboma
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.