Monarch Ortholog Phenotypes
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Mouse (28 sources):
abnormal brain development,
abnormal cerebral cortex morphology,
abnormal CNS synaptic transmission,
abnormal excitatory postsynaptic potential,
abnormal food intake,
abnormal hepatocyte morphology,
abnormal neuron physiology,
abnormal NMDA-mediated synaptic currents,
abnormal object recognition memory,
abnormal response to novel object,
abnormal retrosplenial region morphology,
abnormal small intestinal microvillus morphology,
abnormal spatial learning,
decreased anxiety-related response,
decreased body size,
decreased brain size,
decreased corpus callosum size,
decreased striatum size,
enhanced long term potentiation,
enlarged lateral ventricles,
impaired balance,
nervous system phenotype,
postnatal lethality,
premature death,
reduced long term depression,
skeletal muscle fiber atrophy,
thin cerebral cortex,
weakness
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