gdap1 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (63)

Interactants (42)

XB-GENEPAGE-978241

Gene Symbol: gdap1 Gene Name: ganglioside induced differentiation associated protein 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gdap1 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (41 sources): Areflexia, Arrhythmia, Axonal degeneration, Axonal degeneration/regeneration, Axonal regeneration, Basal lamina onion bulb formation, CNS hypomyelination, Decreased motor nerve conduction velocity, Decreased nerve conduction velocity, Decreased number of large peripheral myelinated nerve fibers, Decreased number of peripheral myelinated nerve fibers, Distal amyotrophy, Distal muscle weakness, Distal sensory impairment, EMG: neuropathic changes, Flexion contracture, Foot dorsiflexor weakness, Gait disturbance, Hammertoe, Hand muscle atrophy, Hypertrophic nerve changes, Hyporeflexia, Inability to walk by childhood/adolescence, Kyphoscoliosis, Limb muscle weakness, Motor delay, Onion bulb formation, Peripheral axonal degeneration, Peripheral demyelination, Peripheral hypomyelination, Peripheral neuropathy, Pes cavus, Proximal muscle weakness, Scoliosis, Skeletal muscle atrophy, Spinal deformities, Split hand, Steppage gait, Talipes equinovarus, Ulnar claw, Vocal cord paresis [+]
Mouse (23 sources): abnormal action potential, abnormal axon extension, abnormal axonal transport, abnormal calcium ion homeostasis, abnormal dorsal root ganglion morphology, abnormal endoplasmic reticulum morphology, abnormal epididymis morphology, abnormal neurite morphology, abnormal neuromuscular synapse morphology, abnormal seminal vesicle morphology, abnormal thymus morphology, cellular phenotype, chromatolysis, enlarged epididymis, increased mitochondrial DNA content, increased mitochondrial size, limb grasping, nervous system phenotype, oxidative stress, short stride length, small adrenal glands, small superior vagus ganglion, small thymus [+]
View all ortholog results at Monarch