tfam Phenotypes

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Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (39 sources): abnormal PNS glial cell morphology, abnormal blood flow velocity, abnormal colon morphology, abnormal dopaminergic neuron morphology, abnormal enteric neuron morphology, abnormal enzyme/coenzyme level, abnormal heart development, abnormal limb posture, abnormal mitochondrial ATP synthesis coupled electron transport, abnormal respiratory electron transport chain, abnormal somite development, absent pancreatic beta cells, cellular phenotype, decreased body size, decreased dopamine level, decreased exploration in new environment, decreased insulin secretion, decreased locomotor activity, decreased mitochondrial DNA content, decreased neuron number, dilated heart atrium, dilated heart left ventricle, disorganized mitochondrial cristae, embryonic lethality during organogenesis, complete penetrance, impaired skeletal muscle contractility, increased apoptosis, increased cardiomyocyte apoptosis, increased glutathione peroxidase activity, increased heart weight, increased insulin sensitivity, increased mitochondrial size, increased physiological sensitivity to xenobiotic, increased skeletal muscle fiber size, loss of dopaminergic neurons, neonatal lethality, incomplete penetrance, neuron degeneration, neuronal intranuclear inclusions, postnatal lethality, complete penetrance, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (39 sources): abnormal PNS glial cell morphology, abnormal blood flow velocity, abnormal colon morphology, abnormal dopaminergic neuron morphology, abnormal enteric neuron morphology, abnormal enzyme/coenzyme level, abnormal heart development, abnormal limb posture, abnormal mitochondrial ATP synthesis coupled electron transport, abnormal respiratory electron transport chain, [+]