| Monarch Ortholog Phenotypes
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Human (4 sources):
Follicular hyperkeratosis,
Hyperkeratotic papule,
Hypomelanotic macule,
Reticular hyperpigmentation
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Mouse (38 sources):
abnormal atrioventricular cushion morphology,
abnormal bronchiole epithelium morphology,
abnormal cardiac epithelial to mesenchymal transition,
abnormal dorsal-ventral polarity of the somites,
abnormal heart development,
abnormal mammary gland growth during pregnancy,
abnormal somite development,
abnormal somite shape,
abnormal somite size,
abnormal vasculogenesis,
abnormal vertebral column morphology,
abnormal vitelline vasculature morphology,
absent club cells,
absent intersomitic vessels,
absent vertebral spinous process,
absent vitelline blood vessels,
decreased birth body size,
decreased body length,
decreased body size,
decreased embryo size,
distended pericardium,
embryo phenotype,
embryonic growth retardation,
embryonic lethality during organogenesis,
embryonic lethality during organogenesis, complete penetrance,
epidermal cyst,
failure of heart looping,
fused somites,
increased solitary pulmonary neuroendocrine cell number,
kinked neural tube,
kinked tail,
myocardial trabeculae hypoplasia,
postnatal lethality, incomplete penetrance,
premature death,
prenatal lethality,
reproductive system phenotype,
respiratory system phenotype,
short tail
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.