lrp8 Phenotypes

Phenotypes

XB-GENEPAGE-980034

Gene Symbol: lrp8 Gene Name: LDL receptor related protein 8

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: lrp8 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal Purkinje cell morphology, abnormal brain development, abnormal cell death, abnormal cerebral cortex morphology, abnormal contextual conditioning behavior, abnormal dentate gyrus morphology, abnormal hippocampus layer morphology, abnormal hippocampus pyramidal cell layer, abnormal postnatal subventricular zone morphology, abnormal rostral migratory stream morphology, abnormal spatial learning, abnormal spatial reference memory, abnormal sperm flagellum morphology, abnormal sperm midpiece morphology, abnormal sperm mitochondrial sheath morphology, abnormal sperm physiology, asthenozoospermia, coiled sperm flagellum, decreased motor neuron number, hairpin sperm flagellum, kinked sperm flagellum, neuron degeneration, no abnormal phenotype detected, reduced cerebellar foliation, reduced long term potentiation, reduced male fertility, small cerebellum [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal Purkinje cell morphology, abnormal brain development, abnormal cell death, abnormal cerebral cortex morphology, abnormal contextual conditioning behavior, abnormal dentate gyrus morphology, abnormal hippocampus layer morphology, abnormal hippocampus pyramidal cell layer, abnormal postnatal subventricular zone morphology, abnormal rostral migratory stream morphology, [+]