| Monarch Ortholog Phenotypes
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Human (15 sources):
Abnormality of neutrophils,
Atrial fibrillation,
Cardiomyopathy,
Chest pain,
Congestive heart failure,
Dilated cardiomyopathy,
Elevated circulating creatine kinase concentration,
EMG abnormality,
Left ventricular hypertrophy,
Lipoatrophy,
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Mouse (22 sources):
abnormal cardiac muscle contractility,
abnormal cardiac muscle relaxation,
abnormal heart left ventricle pressure,
abnormal myocardial fiber physiology,
abnormal skeletal muscle fiber type ratio,
abnormal soleus morphology,
cardiac interstitial fibrosis,
cardiovascular system phenotype,
decreased soleus weight,
decreased ventricle muscle contractility,
dilated heart left ventricle,
dilated heart ventricle,
enlarged myocardial fiber,
impaired exercise endurance,
impaired skeletal muscle contractility,
increased cardiac muscle contractility,
increased creatine kinase activity,
increased heart weight,
oxidative stress,
premature death,
skeletal muscle endomysial fibrosis,
skeletal muscle fibrosis
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.