| Monarch Ortholog Phenotypes
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Human (22 sources):
Ataxia,
Behavioral abnormality,
Cognitive impairment,
Confusion,
Dementia,
Dysarthria,
Generalized myoclonic seizure,
Hallucinations,
Hyperreflexia,
Lafora bodies,
Mental deterioration,
Mutism,
Myoclonus,
Paranoia,
Progressive cerebellar ataxia,
Psychosis,
Seizure,
Spastic ataxia,
Spastic tetraparesis,
Spastic tetraplegia,
Spasticity,
Urinary incontinence
[+]
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|
Mouse (10 sources):
abnormal axon guidance,
abnormal inspiratory capacity,
abnormal uterus morphology,
absent hippocampal commissure,
decreased caudal vertebrae number,
excessive scratching,
increased airway resistance,
increased lung tissue damping,
nervous system phenotype,
skin lesions
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.