Elevated circulating hepatic transaminase concentration, Emphysema, Failure to thrive in infancy, Gastrointestinal stroma tumor, Hemolytic anemia, Immunodeficiency, Lymphadenopathy, Lymphoma, Lymphopenia, Oral ulcer, Otitis media, Pneumonia, Posterior pharyngeal cleft, Purpura, Recurrent bronchitis, Recurrent infections, Recurrent respiratory infections, Recurrent sinopulmonary infections, Recurrent skin infections, Restrictive ventilatory defect, Splenomegaly, Thrombocytopenia, Vasculitis, obsolete Hypotrichosis

abnormal humoral immune response, abnormal inguinal lymph node morphology, abnormal lymph organ size, abnormal lymphocyte physiology, abnormal macrophage physiology, abnormal professional antigen presenting cell physiology, abnormal skin condition, absent inguinal lymph nodes, cecum inflammation, cochlear ganglion degeneration, decreased B cell proliferation, decreased B-1 B cell number, decreased B-1a cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased IgG1 level, decreased IgG3 level, decreased NK T cell number, decreased Peyer's patch number, decreased T cell proliferation, decreased central memory CD4-positive, alpha-beta T cell number, decreased circulating amylase level, decreased circulating interleukin-2 level, decreased cochlear nerve compound action potential, decreased effector memory CD4-positive, alpha-beta T cell number, decreased erythrocyte cell number, decreased interleukin-1 beta secretion, decreased interleukin-2 secretion, decreased interleukin-4 secretion, decreased interleukin-6 secretion, decreased lean body mass, decreased marginal zone B cell number, decreased mean corpuscular hemoglobin concentration, decreased memory T cell number, decreased myeloid dendritic cell number, decreased osteoclast cell number, decreased regulatory T cell number, decreased respiratory quotient, decreased single-positive T cell number, decreased susceptibility to Picornaviridae infection induced morbidity/mortality, decreased susceptibility to autoimmune diabetes, decreased thermal nociceptive threshold, decreased tumor necrosis factor secretion, enlarged lymph nodes, homeostasis/metabolism phenotype, immune system phenotype, impaired humoral immune response, increased B cell proliferation, increased IgG1 level, increased apoptosis, increased central memory CD8 positive, alpha-beta T cell number, increased circulating alkaline phosphatase level, increased susceptibility to age-related hearing loss, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to induced colitis, increased susceptibility to noise-induced hearing loss, increased thermal nociceptive threshold, lymphoid hyperplasia, muscle phenotype, myeloid hyperplasia, no abnormal phenotype detected, premature death, preweaning lethality, incomplete penetrance, rough coat, skeleton phenotype, small Peyer's patches, small inguinal lymph nodes