Monarch Ortholog Phenotypes
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Mouse (22 sources):
abnormal DNA replication,
abnormal cell cycle checkpoint function,
abnormal channel response,
abnormal cranium morphology,
abnormal ear morphology,
abnormal embryo size,
abnormal neuromuscular synapse morphology,
abnormal synaptic acetylcholine release,
decreased body length,
decreased fetal size,
decreased fibroblast proliferation,
decreased neurotransmitter release,
decreased thymocyte number,
embryo phenotype,
embryonic lethality, complete penetrance,
increased cell mass,
lethality throughout fetal growth and development, complete penetrance,
muscle phenotype,
no abnormal phenotype detected,
prenatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
small thymus
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