Monarch Ortholog Phenotypes
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Mouse (22 sources):
abnormal cell cycle checkpoint function,
abnormal channel response,
abnormal cranium morphology,
abnormal DNA replication,
abnormal ear morphology,
abnormal embryo size,
abnormal neuromuscular synapse morphology,
abnormal synaptic acetylcholine release,
decreased body length,
decreased fetal size,
decreased fibroblast proliferation,
decreased neurotransmitter release,
decreased thymocyte number,
embryonic lethality, complete penetrance,
embryo phenotype,
increased cell mass,
lethality throughout fetal growth and development, complete penetrance,
muscle phenotype,
no abnormal phenotype detected,
prenatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
small thymus
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