Akinesia, Aspiration pneumonia, Ataxia, Attention deficit hyperactivity disorder, Behavioral abnormality, Blepharospasm, Blindness, Bradykinesia, Cachexia, Cerebral degeneration, Chorea, Choreoathetosis, Clumsiness, Cognitive impairment, Compulsive behaviors, Constipation, Cough, Decreased LDL cholesterol concentration, Decreased muscle mass, Dementia, Depression, Developmental regression, Dysarthria, Dysphagia, Dysphonia, Dystonia, Emotional lability, Eye of the tiger anomaly of globus pallidus, Eyelid apraxia, Facial grimacing, Failure to thrive, Feeding difficulties in infancy, Focal dystonia, Frequent falls, Gait disturbance, Gastroesophageal reflux, Generalized dystonia, Global brain atrophy, Global developmental delay, Hyperactivity, Hyperpigmentation of the skin, Hyperreflexia, Impulsivity, Inability to walk, Increased susceptibility to fractures, Inertia, Iris hypopigmentation, Iron accumulation in brain, Irritability, Joint dislocation, Limb dystonia, Mask-like facies, Mental deterioration, Motor tics, Muscle stiffness, Myopathy, Neurodegeneration, Neurological speech impairment, Obsessive-compulsive trait, Opisthotonus, Optic atrophy, Optic disc pallor, Orofacial dyskinesia, Oromandibular dystonia, Palilalia, Pallidal degeneration, Parkinsonism, Pigmentary retinopathy, Psychosis, Recurrent respiratory infections, Retinal degeneration, Retinopathy, Rigidity, Rod-cone dystrophy, Seizure, Spasticity, Tongue atrophy, Tremor, Upper motor neuron dysfunction, Urinary incontinence, Violent behavior, Visual impairment, Weight loss, obsolete Toe walking

reduced female fertility