Acanthocytosis, Akinesia, Aspiration pneumonia, Ataxia, Attention deficit hyperactivity disorder, Atypical behavior, Blepharospasm, Blindness, Bradykinesia, Cachexia, Cerebral degeneration, Chorea, Choreoathetosis, Clumsiness, Cognitive impairment, Compulsive behaviors, Constipation, Cough, Decreased LDL cholesterol concentration, Decreased muscle mass, Dementia, Depression, Developmental regression, Dysarthria, Dysphagia, Dysphonia, Dystonia, Emotional lability, Eyelid apraxia, Eye of the tiger anomaly of globus pallidus, Facial grimacing, Failure to thrive, Feeding difficulties in infancy, Focal dystonia, Frequent falls, Gait disturbance, Gastroesophageal reflux, Generalized dystonia, Global brain atrophy, Global developmental delay, Hyperactivity, Hyperpigmentation of the skin, Hyperreflexia, Impulsivity, Inability to walk, Increased susceptibility to fractures, Inertia, Iris hypopigmentation, Iron accumulation in brain, Irritability, Joint dislocation, Limb dystonia, Mask-like facies, Mental deterioration, Motor tics, Muscle stiffness, Myopathy, Neurodegeneration, Obsessive-compulsive trait, obsolete Toe walking, Opisthotonus, Optic atrophy, Optic disc pallor, Orofacial dyskinesia, Oromandibular dystonia, Palilalia, Pallidal degeneration, Parkinsonism, Pigmentary retinopathy, Psychosis, Recurrent respiratory infections, Retinal degeneration, Retinopathy, Rigidity, Rod-cone dystrophy, Seizure, Spasticity, Tongue atrophy, Tremor, Upper motor neuron dysfunction, Urinary incontinence, Violent behavior, Visual impairment, Weight loss

reduced female fertility