gabrd Phenotypes

Phenotypes

XB-GENEPAGE-988597

Gene Symbol: gabrd Gene Name: gamma-aminobutyric acid (GABA) A receptor, delta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gabrd assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (20 sources): abnormal CNS synaptic transmission, abnormal GABAergic neuron physiology, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal depression-related behavior, abnormal inhibitory postsynaptic currents, abnormal maternal nurturing, abnormal nest building behavior, abnormal pup retrieval, behavioral despair, decreased anxiety-related response, decreased litter size, decreased susceptibility to pharmacologically induced seizures, hearing/vestibular/ear phenotype, impaired ability to fire action potentials, impaired behavioral response to anesthetic, increased anxiety-related response, increased excitatory postsynaptic current amplitude, postnatal lethality, pup cannibalization [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (20 sources): abnormal CNS synaptic transmission, abnormal GABAergic neuron physiology, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal depression-related behavior, abnormal inhibitory postsynaptic currents, abnormal maternal nurturing, abnormal nest building behavior, abnormal pup retrieval, behavioral despair, [+]