| Monarch Ortholog Phenotypes
|
Mouse (28 sources):
abnormal chromosome morphology,
abnormal epidermal pigmentation,
abnormal hepatocyte morphology,
abnormal keratinocyte physiology,
abnormal telomere morphology,
chromosomal instability,
decreased keratinocyte proliferation,
decreased telomere length,
embryonic lethality, complete penetrance,
epidermal atrophy,
epidermal hyperplasia,
focal dorsal hair loss,
hair follicle degeneration,
increased cellular sensitivity to alkylating agents,
increased cellular sensitivity to ultraviolet irradiation,
increased ear pigmentation,
increased foot pigmentation,
increased incidence of tumors by UV-induction,
increased keratoacanthoma incidence,
increased sensitivity to skin irradiation,
increased skin tumor incidence,
increased tail pigmentation,
induced chromosome breakage,
premature aging,
prenatal lethality, incomplete penetrance,
sebaceous gland atrophy,
skin hyperplasia,
skin photosensitivity
[+]
|
These phenotypes are associated with this gene with a has phenotype relation via Monarch.