acer1 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (0)

XB-GENEPAGE-991794

Gene Symbol: acer1 Gene Name: alkaline ceramidase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: acer1 assayed (12 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (42 sources): abnormal awl hair morphology, abnormal ceramide level, abnormal epidermis stratum corneum morphology, abnormal epidermis stratum granulosum morphology, abnormal hair cuticle, abnormal hair cycle, abnormal hair cycle anagen phase, abnormal hair cycle telogen phase, abnormal hair follicle bulge morphology, abnormal hair follicle development, abnormal hair follicle infundibulum morphology, abnormal hair follicle morphology, abnormal hair follicle physiology, abnormal keratohyalin granule morphology, abnormal lipid level, abnormal piliary canal morphology, abnormal sebaceous lipid secretion, abnormal sebocyte morphology, abnormal skin development, abnormal skin sebaceous gland morphology, abnormal sphingomyelin level, abnormal zigzag hair morphology, decreased bone mineral content, decreased brown adipose tissue mass, decreased brown fat cell lipid droplet size, decreased circulating glucose level, decreased epididymal fat pad weight, decreased inguinal fat pad weight, decreased sphingosine level, delayed skin barrier formation, dilated hair follicle infundibulum, enlarged sebaceous gland, epidermal hyperplasia, impaired skin barrier function, increased apoptosis, increased basal metabolism, increased energy expenditure, increased epididymal fat pad weight, increased food intake, increased keratinocyte proliferation, sebaceous gland hypertrophy, thick dermal layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (42 sources): abnormal awl hair morphology, abnormal ceramide level, abnormal epidermis stratum corneum morphology, abnormal epidermis stratum granulosum morphology, abnormal hair cuticle, abnormal hair cycle, abnormal hair cycle anagen phase, abnormal hair cycle telogen phase, abnormal hair follicle bulge morphology, abnormal hair follicle development, [+]