bach2 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (70)

Interactants (45)

XB-GENEPAGE-994312

Gene Symbol: bach2 Gene Name: BTB domain and CNC homolog 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: bach2 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (10 sources): Bronchiectasis, Colitis, Decreased circulating antibody level, Eczema, Inflammation of the large intestine, Pulmonary infiltrates, Recurrent infections, Recurrent otitis media, Recurrent sinopulmonary infections, Splenomegaly
Mouse (60 sources): abnormal bone mineralization, abnormal class switch recombination, abnormal fasting circulating glucose level, abnormal food intake, abnormal grip strength, abnormal locomotor activation, abnormal prepulse inhibition, abnormal pulmonary respiratory rate, abnormal respiratory quotient, abnormal somatic hypermutation frequency, absent germinal center B cells, decreased CD11b-high dendritic cell number, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased IgG3 level, decreased bone mineral content, decreased cardiac stroke volume, decreased circulating glucose level, decreased effector memory CD8-positive, alpha-beta T cell number, decreased fasting circulating glucose level, decreased follicular B cell number, decreased food intake, decreased grip strength, decreased marginal zone B cell number, decreased mature B cell number, decreased memory-marker NK cell number, decreased prepulse inhibition, decreased regulatory T cell number, decreased respiratory quotient, decreased vertical activity, increased B-1 B cell number, increased CD103-positive CD11b-low dendritic cell number, increased CD11b-low dendritic cell number, increased CD4-positive, alpha-beta memory T cell number, increased CD8-positive, alpha-beta memory T cell number, increased KLRG1+ CD4 alpha beta T cell number, increased KLRG1+ CD8 alpha beta T cell number, increased KLRG1-positive CD4-negative NK T cell number, increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased KLRG1-positive NK cell number, increased KLRG1-positive gamma-delta T cell number, increased Ly6C high monocyte number, increased Ly6C low monocyte number, increased NK cell number, increased circulating unsaturated transferrin level, increased effector memory CD8-positive, alpha-beta T cell number, increased effector memory T-helper cell number, increased grip strength, increased immature B cell number, increased macrophage cell number, increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased memory-marker CD4-negative NK T cell number, increased memory-marker NK cell number, increased neutrophil cell number, increased pulmonary respiratory rate, limb grasping, myeloid hyperplasia [+]
View all ortholog results at Monarch