sorl1 Phenotypes

Phenotypes

XB-GENEPAGE-995775

Gene Symbol: sorl1 Gene Name: sortilin-related receptor, L(DLR class) A repeats containing

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (26 sources): Abnormality of mental function, Abnormality of vision, Abnormal social behavior, Agitation, Aphasia, Apraxia, Ataxia, Cerebral cortical atrophy, Confusion, Dementia, Deposits immunoreactive to beta-amyloid protein, Disinhibition, Dysgraphia, Finger agnosia, Hallucinations, Intellectual disability, Language impairment, Memory impairment, Myoclonus, Neurodevelopmental abnormality, Neurofibrillary tangles, Oculomotor apraxia, Parkinsonism, Seizure, Semantic dementia, Spasticity [+]
Mouse (13 sources): abnormal cholinergic neuron morphology, abnormal fasting circulating glucose level, abnormal object recognition memory, abnormal snout morphology, abnormal vascular smooth muscle physiology, abnormal vascular wound healing, amyloid beta deposits, enlarged seminal vesicle, impaired spatial learning, increased fasting circulating glucose level, nervous system phenotype, neuron degeneration, tau protein deposits [+]
View all ortholog results at Monarch