usp18 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (73)

Interactants (23)

XB-GENEPAGE-996277

Gene Symbol: usp18 Gene Name: ubiquitin specific peptidase 18

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: usp18 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources): Ascites, Bradycardia, Cerebellar hypoplasia, Cerebral calcification, Cerebral hemorrhage, Decreased liver function, Elevated circulating hepatic transaminase concentration, Generalized hypotonia, Gray matter heterotopia, Hepatomegaly, Lactic acidosis, Lethargy, Microcephaly, Patent ductus arteriosus, Petechiae, Polymicrogyria, Respiratory insufficiency, Seizure, Thrombocytopenia, Ventriculomegaly [+]
Mouse (17 sources): abnormal cerebral cortex morphology, abnormal cytokine level, circling, convulsive seizures, decreased circulating interferon-alpha level, decreased circulating interferon-beta level, decreased circulating interferon-gamma level, decreased interferon-gamma secretion, decreased susceptibility to Coronaviridae infection, enlarged lateral ventricles, enlarged third ventricle, increased circulating interleukin-6 level, increased interleukin-6 secretion, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to endotoxin shock, premature death, spinning [+]
View all ortholog results at Monarch