Apathy, Ataxia, Babinski sign, Blepharospasm, Bowel incontinence, Bradykinesia, Cerebellar atrophy, Cerebral cortical atrophy, Cognitive impairment, Confusion, Dementia, Depression, Difficulty in tongue movements, Difficulty walking, Diffuse cerebral atrophy, Distal sensory impairment, Dysarthria, Dyskinesia, Dysphagia, Dystonia, EMG: axonal abnormality, Eyelid apraxia, Facial myokymia, Fatigue, Fever, Gait disturbance, Generalized muscle weakness, Hallucinations, Horizontal nystagmus, Hyperactive patellar reflex, Hyperreflexia, Hyperreflexia in upper limbs, Hypomimic face, Hypoplasia of the corpus callosum, Hyposmia, Leg muscle stiffness, Lethargy, Lingual dystonia, Lower limb hyperreflexia, Mask-like facies, Mental deterioration, Muscle weakness, Myoclonus, Neurogenic bladder, Nystagmus, Oculogyric crisis, Paraparesis, Parkinsonism, Parkinsonism with favorable response to dopaminergic medication, Peripheral axonal neuropathy, Pes cavus, Postural instability, Postural tremor, Progressive cerebellar ataxia, Progressive extrapyramidal movement disorder, Progressive gait ataxia, Progressive pes cavus, Progressive spastic paraplegia, Progressive spastic quadriplegia, Psychotic episodes, Rigidity, Seizure, Sensory axonal neuropathy, Short attention span, Slow saccadic eye movements, Spastic paraplegia, Spastic tetraplegia, Spasticity, Stooped posture, Strabismus, Supranuclear gaze palsy, Torticollis, Tremor, Upgaze palsy, Upper motor neuron dysfunction, Urinary incontinence, Vertical supranuclear gaze palsy, Visual hallucinations

lysosomal protein accumulation, nervous system phenotype, short stride length