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Summary Expression Phenotypes Gene Literature (12) GO Terms (6) Nucleotides (48) Proteins (28) Interactants (153) Wiki

tph1     tryptophan hydroxylase 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tph1 assayed (4 sources)
Computed annotations: tph1 assayed (6 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (16 sources): abnormal heart left ventricle pressure, abnormal serotonin level, behavior/neurological phenotype, decreased cardiac muscle contractility, decreased cardiac output, decreased cardiac stroke volume, decreased pancreatic beta cell mass, decreased pancreatic beta cell proliferation, decreased physiological sensitivity to xenobiotic, decreased serotonin level, [+]