Monarch Ortholog Phenotypes
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Mouse (46 sources):
abnormal AMPA-mediated synaptic currents,
abnormal CNS synaptic transmission,
abnormal NMDA-mediated synaptic currents,
abnormal adipose tissue amount,
abnormal anxiety-related response,
abnormal bone mineralization,
abnormal contextual conditioning behavior,
abnormal dendritic spine morphology,
abnormal discrimination learning,
abnormal glutamate-mediated receptor currents,
abnormal hippocampus pyramidal cell morphology,
abnormal innervation,
abnormal lean body mass,
abnormal learning/memory/conditioning,
abnormal maternal nurturing,
abnormal nociception after inflammation,
abnormal pain threshold,
abnormal sebaceous gland morphology,
abnormal social investigation,
abnormal spatial learning,
abnormal spatial working memory,
abnormal synaptic plasticity,
decreased anxiety-related response,
decreased body size,
decreased grip strength,
decreased locomotor activity,
decreased neurotransmitter release,
decreased startle reflex,
decreased stereotypic behavior,
decreased vertical activity,
decreased vocalization,
enhanced behavioral response to cocaine,
enhanced long term potentiation,
enhanced paired-pulse facilitation,
impaired balance,
impaired behavioral response to cocaine,
increased anxiety-related response,
increased bone mineral content,
increased grip strength,
increased grooming behavior,
increased lean body mass,
increased response to stress-induced hyperthermia,
maternal effect,
nervous system phenotype,
postnatal lethality, incomplete penetrance,
reduced AMPA-mediated synaptic currents
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