abnormal hypoglossal nerve topology, abnormal immunoglobulin heavy chain V(D)J recombination, abnormal lymphatic vessel topology, abnormal neuron differentiation, abnormal optic cup morphology, abnormal pulmonary alveolus morphology, abnormal somatic hypermutation frequency, abnormal spleen germinal center morphology, abnormal vagus ganglion morphology, abnormal vertebral artery topology, abnormal vitelline vein connection, absent extracranial vertebral artery segment, absent stapedial artery, chromosomal instability, decreased birth weight, decreased body size, decreased cell proliferation, decreased fibroblast proliferation, dermal cyst, dermatitis, dorsal root ganglion hyperplasia, dorsal root ganglion hypoplasia, embryonic growth retardation, enlarged cervical lymph nodes, enlarged salivary gland, fusion of vertebral arches, immune system phenotype, increased T-helper 2 cell number, increased anti-nuclear antigen antibody level, increased bone mineral content, increased embryonic tissue cell apoptosis, increased germinal center B cell number, increased heart weight, increased hepatocyte apoptosis, increased kidney apoptosis, increased lean body mass, increased neuron apoptosis, increased red blood cell distribution width, increased sensitivity to induced cell death, increased spleen germinal center number, increased splenocyte apoptosis, increased susceptibility to systemic lupus erythematosus, increased trigeminal neuroma incidence, inverse situs of great intrathoracic arteries, neonatal lethality, complete penetrance, neonatal lethality, incomplete penetrance, perinatal lethality, complete penetrance, persistent trigeminal artery, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, reduced sympathetic cervical ganglion size, retro-esophageal left subclavian artery, salivary gland inflammation, small superior cervical ganglion, small superior vagus ganglion, small thyroid gland, subcutaneous edema, thin cerebral cortex, thin facial nerve, thin hypoglossal nerve, thin motoric part of trigeminal nerve, thin oculomotor nerve, thin splanchnic nerve