The gene drc12 encodes a structural protein component of the axonemal dynein regulatory complex within motile cilia. Its function is associated with proper ciliary beating and motility in multiciliated...[+]

The gene drc12 encodes a structural protein component of the axonemal dynein regulatory complex within motile cilia. Its function is associated with proper ciliary beating and motility in multiciliated epithelial cells, particularly those found in the epidermis and the mucociliary epithelium of the pronephros. The drc12 protein localizes to the axoneme and cytoplasm. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD