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XB-GENEPAGE-988967
Gene Symbol: apaf1
Gene Name: apoptotic peptidase activating factor 1
Synonyms:
apaf-1
(
Gene Function: apoptosis/apoptosome scaffold protein with WD-40 domains, caspase recruitment domain (CARD), and an ATPase domain Protein Function
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Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
Interactants:
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Diseases: External Links:
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Expression | Development Stages Embryonic Tissues Adult Tissues | |||||||||||
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